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VAP-1 (Vascular Adhesion Protein 1, Membrane Primary Amine Oxidase, Copper Amine Oxidase, HPAO, Semicarbazide-sensitive Amine Oxidase, SSAO, VAP1)

VAP-1 (Vascular Adhesion Protein 1, Membrane Primary Amine Oxidase, Copper Amine Oxidase, HPAO, Semicarbazide-sensitive Amine Oxidase, SSAO, VAP1)

Cat no: V2095-03B

Supplier: United States Biological
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Vascular adhesion protein 1 (VAP-1), also known as AOC3 (amine oxidase copper-containing 3) or SSAO (semicarbazide-sensitive amine oxidase) is a 170 kD type II transmembrane glycoprotein consisting of two disulfide-linked 763aa subunits. It is expressed on endothelium, vascular smooth muscle, and adipocytes. The extracellular domain mediates lymphocyte rolling, adhesion, possibly extravasations during inflammation, and possesses monoamine oxidase activity. Adipocytes can release a soluble form via metalloproteinase cleavage. Human VAP-1 ECD shares 83% and 88% aa sequence identity with mouse and canine VAP-1 ECD, respectively. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 3-5ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human Liver Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: V2095-03B
Reactivities: Human
Hosts: Goat
Applications: Immunohistochemistry
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human VAP-1. Species sequence homology: mouse and rat.

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