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Vascular Endothelial Growth Factor, Mature (VEGF-C, VEGF-A, Vascular permeability factor, VPF)

Cat no: V2121-30G

Vascular Endothelial Growth Factor, Mature (VEGF-C, VEGF-A, Vascular permeability factor, VPF)

Vascular endothelial growth factors (VEGFs), a group of structurally and functionally related growth factors, may play important roles in vascular system formation during embryonic development, the regulation of capillary growth in adults, and the maintenance of normal vasculature. It is a ligand for the receptor tyrosine kinases VEGFR-3 and VEGFR2, both of which are expressed by endothelial cells. VEGF-C mRNA has been detected in human heart, placenta, muscle, ovary, and small intestine, as well as in malignant tissues. In addition, VEGF-C mRNA expression was detected in over 50% of tumor specimens studied.\n\nApplications:\nSuitable for use in Western Blot.\nOther applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1: 500\nOptimal dilutions to be determined by the researcher.\n\nPositive Control:\nHUVEC cell lysate.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

V2121-30G

Size

100ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.

P Type

Pab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG

Additional Info

Recognizes human VEGF-C (Mature). Species Crossreactivity: mouse, rat.

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