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Vascular Endothelial Growth Factor Receptor 1 (VEGF Receptor 1, VEGFR 1, VEGFR1, VEGFR-1, EC 2.7.10.1, FLT, Fms-like Tyrosine Kinase 1, Flt 1, Flt1, Flt-1, Fms Related Tyrosine Kinase 1, Fms-related Tyrosine Kinase 1 (Vascular Endothelial Growth Factor/Va

Cat no: V2110-16L

Vascular Endothelial Growth Factor Receptor 1 (VEGF Receptor 1, VEGFR 1, VEGFR1, VEGFR-1, EC 2.7.10.1, FLT, Fms-like Tyrosine Kinase 1, Flt 1, Flt1, Flt-1, Fms Related Tyrosine Kinase 1, Fms-related Tyrosine Kinase 1 (Vascular Endothelial Growth Factor/Va

VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity. Because sFLT1 has a higher affinity for VEGF than does FLK1, it may function as an inhibitor of VEGF response.\n\nApplications: \nSuitable for use in ELISA and Immunoprecipitation. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nCellular Localization: Type I membrane protein (Flt1) and soluble (SFlt1).\n\nStorage and Stability:\nLyophilized powder may be stored at 4 degrees C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degrees C. Reconstituted product is stable for 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

V2110-16L

Size

200ug

Applications

ELISA, IP

Hosts

Rabbit

Reactivities

Hum

Form

Lyophilized. PBS w/o preservative

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

Additional Info

Species Crossreactivity: Crossreacts with Human.

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