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Vascular Endothelial Growth Factor Receptor 1 (VEGFR-1, FLT-1)

Vascular Endothelial Growth Factor Receptor 1 (VEGFR-1, FLT-1)

Cat no: V2110-16D

Supplier: United States Biological
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VEGFR-1 is a type I membrane protein. This protein binds VEGF, PLGF and VEGFB and belongs to the tyrosine protein kinase family. VEGFR-1 has a signaling role in mediating monocyte chemotaxis in tumor disease and performs an inhibitory role by sequestering VEGF and preventing its interaction with VEGFR-2. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilutions: ELISA: 1:8000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: V2110-16D
Reactivities: Human
Hosts: Mouse
Applications: ELISA
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.2.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
References: 1. Ferrara, N., et al., Nat. Med. 9: 669-676 (2003). 2. Cross, M.J., et al., Trends Biochem. Sci. 28: 488-494 (2003).
Additional info: Recognizes extracellular domain of human VEGFR-1.

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