Home  >  Products  >  Vascular Endothelial Growth Factor (VEGF, Vegf120, Vegf164, Vegf188, Vascular Endothelial Growth Factor A, Vegfa, VEGF-A, Vascular Permeability Factor, VPF)

Vascular Endothelial Growth Factor (VEGF, Vegf120, Vegf164, Vegf188, Vascular Endothelial Growth Factor A, Vegfa, VEGF-A, Vascular Permeability Factor, VPF)

Cat no: V2110-11E


Supplier: United States Biological
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VEGF (vascular endothelial growth factor) is a heparin-binding cytokine and member of the PDGF/VEGF growth factor family, which exists as several splice variants of the VEGF gene. VEGF, originally named vascular permeability factor due to its ability to act as vasodilator and increase microvascular permeability, is a potent stimulator of angiogenesis of both normal and cancerous cells, and acts as a regulator of vasculogenesis. The functional forms of VEGF exist as disulphide-linked homodimers and are classified according to the number of amino acid residues within a constitutive polypeptide chain e.g VEGF165. All VEGF family members act through binding to the tyrosine kinase receptors VEGFR-1 (Flt-1) and VEGFR-2 (KDR/CD309), whilst the closely-related VEGF-C and VEGF-D, can also bind to VEGFR-3 (Flt-4). Applications: Suitable for use in Western Blot. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: V2110-11E
Reactivities: Human, Mouse, Rat
Hosts: Mouse
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.6, 0.09% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by affinity chromatography.
Additional info: Recognizes mouse VEGF. Species crossreactivity: human, rat.

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