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WRNIP1 (ATPase WRNIP1, WHIP, Werner Helicase-interacting Protein 1)

WRNIP1 (ATPase WRNIP1, WHIP, Werner Helicase-interacting Protein 1)

Cat no: W1024-80A

Supplier: United States Biological
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WHIP Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. Werner helicase interacting protein 1 (WHIP) interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 1-3ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: W1024-80A
Reactivities: Human, Mouse, Rat, Bovine, Canine
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Kawabe Yi, Branzei D, Hayashi T, Suzuki H, Masuko T, Onoda F, Heo SJ, Ikeda H, Shimamoto A, Furuichi Y, Seki M, Enomoto T. A novel protein interacts with the Werner's syndrome gene product physically and functionally. J Biol Chem. 2001 Jun 8;276(23):20364-9. Epub 2001 Apr 11.
Additional info: Recognizes human WRNIP1. Species sequence homology: Bovine, canine, mouse and rat.

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