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XAB2 (Pre-mRNA-splicing factor SYF1, XPA-binding Protein 2, Protein HCNP, HCNP, KIAA1177, SYF1)

XAB2 (Pre-mRNA-splicing factor SYF1, XPA-binding Protein 2, Protein HCNP, HCNP, KIAA1177, SYF1)

Cat no: X0801-01B

Supplier: United States Biological
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A novel protein designated XAB2 (XPA-binding protein 2) interacts with XPA, a factor central to both nucleotide excision repair subpathways. Data suggests that XAB2 is a novel component involved in transcription-coupled repair and transcription. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:8000 Western Blot: 0.3-1ug/ml, observed in human fibroblast A431 lysates on ~90kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: X0801-01B
Reactivities: Human, Mouse, Rat, Bovine, Canine
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Nakatsu Y, Asahina H, Citterio E, Rademakers S, Vermeulen W, Kamiuchi S, Yeo JP, Khaw MC, Saijo M, Kodo N, Matsuda T, Hoeijmakers JH, Tanaka K. XAB2, a novel tetratricopeptide repeat protein involved in transcription-coupled DNA repair and transcription. J Biol Chem. 2000 Nov 10;275(45):34931-7.
Additional info: Recognizes human XAB2. Species sequence homology: Bovine, canine, mouse and rat.

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