Cayman's Autophagy/Cytotoxicity Dual Staining provides a convenient tool for studying the regulation of autophagy and cytotoxicity at the cellular level. The...
ATF2 is a sequence-specific DNA-binding protein belonging to the bZIP family of transcription factors that bind with high affinity to the octameric CRE. ATF2...
Cayman's 7-AAD/CFSE Cell-Mediated Cytotoxicity Assay employs CFSE to label target cells and 7-AAD to label dead cells. The labeling distinguishes four...
Mammalian sEH is a member of the (alpha)/(beta)-hydrolase fold family of enzymes that catalyze the hydrolysis of exogenous and endogenous epoxides to vicinal...
Accumulation of the (beta)-amyloid peptide (A(beta)) in the brain is implicated as the primary cause of neurodegeneration and progression of Alzheimer's...
Cayman's p53 Total and p53 (Phospho-Ser392) Dual Staining Assay provides a pair of highly specific antibodies against total and phospho-p53 (Phospho-Ser392)...
It is well established that H2O2 is a cytotoxic agent but evidence also suggests that H2O2 may be an important regulator of eukaryotic signal transduction....
Cayman's p53 Designer Transcription Factor Assay is designed to study alternate p53 DNA-binding sites. A biotinylated oligonucleotide is incubated with p53...
The tumor suppressor protein p53 plays a crucial role in coordinating cellular responses to genotoxic stress and holds many important clinical implications...
The tumor suppressor protein p53 plays a crucial role in coordinating cellular responses to genotoxic stress and holds many important clinical implications...
PGD2 is synthesized by H-PGDS in mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. H-PGDS is therefore a key target...
Albumin (rat) EIA is a competitive assay that can be used for quantification of albumin in rat urine samples. The EIA typically displays an IC50 (50% B/B0)...
Prolactin is a 199 amino acid (23 kDa) neuropeptide best known for its role in the initiation and maintenance of lactation. The hormone is secreted by the...
Cayman's Histamine EIA is a derivitization-amplified competitive enzyme immunoassay which detects histamine within the range from 40 to 5,500 pg/ml. The...
GH is a polypeptide hormone with a molecular weight of 23 kDa released from somatotropes of the anterior pituitary. It is regulated by several...
Insulin is a polypeptide hormone with a molecular weight of 6 kDa, composed of two peptides chains, A and B, cross-linked by two disulfide bonds and...
AcSDKP is a tetrapeptide growth regulatory hormone which inhibits the proliferation of hematopoietic stem cells. The dipeptidase angiotensin converting...
Atriopeptin is a 28 amino acid peptide synthesized primarily in cardiac atria. This peptide hormone acts in opposition to angiotensin II in regulating renal,...
DNA methylation is an important epigenetic process regulating gene expression. Methylation occurs on carbon 5 of 2-deoxy cytidine yielding the modified base...
Both DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer. The repair processes that are initiated to...