Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through...
N-methyl D-aspartate receptor subtype 2C (NMDAR2C) is an NMDA receptor subtype of glutamate-gated ion channels that possesses high calcium permeability and...
N-methyl D-aspartate receptor subtype 2C (NMDAR2C) is an NMDA receptor subtype of glutamate-gated ion channels that possesses high calcium permeability and...
Interferon-a Receptor, Type I, Subunit I (IFNAR1) associates with IFNAR2 to form the type I interferon receptor. This interferon receptor is a receceptor for...
Tau protein promotes microtubule assembly and stability. Tau is also involved in the establishment and maintenance of neural polarity. The C-terminus domain...
Synapsin I plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of...
Tryptophan 5-hydro, Xenopus/Amphibian,ylase 1 (TPH) catalyzes the following reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydro,...
PDZ domain-containing proteins, such as PSD-95 and GRIP, are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs)...
Serine/threonine-protein kinase PAK-1 (PAK-1) is a protein kinase that acts on a variety of targets. PAK-1 is the GTPase effector that links the Rho-related...
MEK1 (MAPKK1) catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. MEKI (MAPKK1)...
Protein phosphatase 1 regulatory subunit 1B (DARPP-32) is e, Xenopus/Amphibian,pressed in dopaminergic neurons. DARPP-32 is a dopamine and cyclic-AMP...
Alpha synuclein is involved in the regulation of dopamine release and transport. Alpha synuclein is only in brain (hippocampus, brainstem and corte,...
DOPA decarbo, Xenopus/Amphibian,ylase (DDC) catalyzes the decarbo, Xenopus/Amphibian,ylation of L-3, 4-dihydro, Xenopus/Amphibian,yphenylalanine (DOPA) to...
DOPA decarbo, Xenopus/Amphibian,ylase (DDC) catalyzes the decarbo, Xenopus/Amphibian,ylation of L-3, 4-dihydro, Xenopus/Amphibian,yphenylalanine (DOPA) to...
Dopamine beta hydro, Xenopus/Amphibian,ylase (DBH) catalyzes the conversion of dopamine to noradrenaline. Defects in DBH are the cause of dopamine...
Tryptophan 5-hydro, Xenopus/Amphibian,ylase 1 (TPH) catalyzes the following reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydro,...
The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP...
14-3-3 protein beta/alpha (14-3-3) is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways....
Mitogen-activated protein kinase p38 alpha (p38 MAPK) responds to activation by environmental stress,Porcinero-inflammatory cytokines and lipopolysaccharide...