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Molecular Biology

Molecular Biology
Small Molecule Actives Identification and Quantification
Small Molecule Actives Identification and Quantification
MtoZ Biolabs

Small molecule drugs, predominantly chemically synthesized drugs with molecular weight lower than 1000 Da. These drugs are characterized by their widespread...

Single-Cell Transcriptome Analysis Service
Single-Cell Transcriptome Analysis Service
MtoZ Biolabs

Humans are highly organized systems comprised of approximately 3.72x1013 cells of various types, which maintain proper organ function and normal cellular...

Glycosylation Quantitative Proteomic Analysis Service
Glycosylation Quantitative Proteomic Analysis Service
MtoZ Biolabs

Glycosylation is a common type of post-translational modification (PTM) involving the covalent bonding of oligosaccharide chains to polypeptide chains. The...

Phosphorylation Quantitative Proteomic Analysis Service
Phosphorylation Quantitative Proteomic Analysis Service
MtoZ Biolabs

Phosphorylation is the most common type of post-translational modification (PTM) that proteins undergo throughout their lifespan. The reversibility and...

Ubiquitination Quantitative Proteomic Analysis Service
Ubiquitination Quantitative Proteomic Analysis Service
MtoZ Biolabs

Ubiquitin (Ub), a small molecule protein composed of 76 amino acids with a molecular weight of approximately 8.5 kDa, is highly conserved throughout...

Single-Cell Mass Cytometry Analysis Service
Single-Cell Mass Cytometry Analysis Service
MtoZ Biolabs

Mass cytometry (CyTOF) uses specific metal isotope-labeled antibodies to mark signal molecules on and inside the cell surfaces. Cells, in the form of...

Activity-Based Protein Profiling (ABPP) Service
Activity-Based Protein Profiling (ABPP) Service
MtoZ Biolabs

Activity-based protein profiling (ABPP) is a versatile and powerful chemoproteomic technique, utilizing activity-based probes (ABPs) that selectively and...

Drug Affinity Responsive Target Stability Analysis Service
Drug Affinity Responsive Target Stability Analysis Service
MtoZ Biolabs

Drug affinity responsive target stability is a label-free small molecule probe technique under chemical proteomics first proposed by Lomenick et al. in 2009,...

Thermal Proteome Profiling (TPP) Service
Thermal Proteome Profiling (TPP) Service
MtoZ Biolabs

Thermal proteome profiling is a combination of cellular thermal shift assay and mass spectrometry, so it is also called MS-CETSA. Thermal proteomic profiling...

Stability of Proteins From Rates of Oxidation Analysis Service
Stability of Proteins From Rates of Oxidation Analysis Service
MtoZ Biolabs

To explore the local conformational function of proteins in relation to their native structural stability, Fitzgerald et al. developed a technique that...

Protein Structures and Interactions Analysis Service | Lip-MS
Protein Structures and Interactions Analysis Service | Lip-MS
MtoZ Biolabs

Limited proteolysis mass spectrometry (LiP-MS) has some of the same mechanisms as DARTS. LiP-MS is a newly developed proteomics approach that combines finite...

HCP Assay Kit Development Service
HCP Assay Kit Development Service
MtoZ Biolabs

Commercial ELISA kits play a crucial role in the preliminary phases of drug development. These kits are applicable to drugs already on the market, provided...

mRNA 5' Capping Rate Analysis Service
mRNA 5' Capping Rate Analysis Service
MtoZ Biolabs

mRNA vaccines offer numerous benefits, including cost-effectiveness, significant R&D flexibility, high manufacturing efficiency, exceptional safety profiles,...

Native Mass Spectrometry Analysis Service
Native Mass Spectrometry Analysis Service
MtoZ Biolabs

Native mass spectrometry (Native MS) facilitates direct determination of a protein's molecular weight. It facilitates the study of intact proteins,...

Tumor-Associated Antigens 2 Screening Service
Tumor-Associated Antigens 2 Screening Service
MtoZ Biolabs

T cells play a vital role in destroying pathogens and monitoring pathological cells. They are able to distinguish between self-antigens and non-self-antigens...

Tumor-Associated Antigens 1 Screening Service
Tumor-Associated Antigens 1 Screening Service
MtoZ Biolabs

T cells play a vital role in destroying pathogens and monitoring pathological cells. They are able to distinguish between self-antigens and non-self-antigens...

Tumor-Associated Antigens Identification Service
Tumor-Associated Antigens Identification Service
MtoZ Biolabs

To accelerate the development of cancer immunotherapy, it is essential to systematically identify tumor antigens that are truly tumor-specific,...

Small Molecule Drug Screening Service-Receptor Categories
Small Molecule Drug Screening Service-Receptor Categories
MtoZ Biolabs

Receptors are biomolecules that can bind with hormones, neurotransmitters, drugs, or intracellular signaling molecules and are capable of inducing changes in...

Small Molecule Drug Screening Service-Ion Channels
Small Molecule Drug Screening Service-Ion Channels
MtoZ Biolabs

Ion channels are made up of special proteins produced by cells, which are aggregated and embedded in the cell membrane, forming pores occupied by water...

Small Molecule Drug Screening Service-Enzymes
Small Molecule Drug Screening Service-Enzymes
MtoZ Biolabs

Kinases, in simple terms, are enzymes that transfer the phosphate groups of ATP to substrates. Kinases catalyze the transfer of ?-phosphate groups of ATP to...

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