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LAT, a transmembrane adaptor protein expressed in T, NK and mast cells, is an important mediator for T cell receptor (TCR) signaling. Upon TCR engagement,...
The vitamin D receptor (VDR), also known as the calcitriol receptor, and also known as NR1I1 (nuclear receptor subfamily 1, group I, member 1), is a member...
The major translational products of each of the eight members of the Src gene family identified to date are membrane-associated tyrosine protein kinases that...
Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6...
Three isoforms of serine/threonine kinases, designated alphaPAK p68, betaPAK p65 and gamma PAK p62, have been shown to exhibit a high degree of sequence...
Three isoforms of serine/threonine kinases, designated alphaPAK p68, betaPAK p65 and gamma PAK p62, have been shown to exhibit a high degree of sequence...
Three isoforms of serine/threonine kinases, designated alphaPAK p68, betaPAK p65 and gamma PAK p62, have been shown to exhibit a high degree of sequence...
p70 S6 kinase is a mitogen activated Ser/Thr protein kinase that is required for cell growth and G1 cell cycle progression. p70 S6 kinase phosphorylates the...
MSK-1 is a mitogen and stress activated protein kinase-1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6...
Mitogen Activated Protein Kinase Kinase 7 (MEK 7 or MKK 7) is a 38 kDa member of a tyrosine/threonine protein kinase family that activates the c Jun...
The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinaseegulatory threonine and tyrosine...
Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6...
The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular beta subunit and an extracellular alpha subunit, which is disulfide-...
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of...
Ephrin receptors bind members of the ephrin ligand family. They are divided into 2 groups based on the similarity of their extracellular domain sequences and...
The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII...
Raf-1 is a cytoplasmic protein with intrinsic serine/threonine activity. It is broadly expressed in nearly all cell lines tested to date and is the cellular...
Tau, also known as MAPT (microtubule-associated protein tau), MAPTL, MTBT1 or TAU, is a 758 amino acid protein that localizes to the cytoplasm, as well as to...
Tau, also known as MAPT (microtubule-associated protein tau), MAPTL, MTBT1 or TAU, is a 758 amino acid protein that localizes to the cytoplasm, as well as to...
The retinoblastoma tumor suppressor gene product, known as Rb or pRb, regulates differentiation, apoptosis and cell cycle control by coordinating the cell...
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