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VDR (K45) Peptide

Cat no: BS3756P

VDR (K45) Peptide

The vitamin D receptor (VDR), also known as the calcitriol receptor, and also known as NR1I1 (nuclear receptor subfamily 1, group I, member 1), is a member of the nuclear receptor family of transcription factors. Upon activation by vitamin D, the VDR forms a heterodimer with the retinoid-X receptor and binds to hormone response elements on DNA resulting in expression or trans-repression of specific gene products.It is an intracellular hormone receptor that specifically binds 1,25(OH)2D3 and mediates its effects. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer.

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SPECIFICATIONS

Catalog Number

BS3756P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide VDR (K45). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P11473

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS3756 VDR (K45) pAb.

Alternative Names

VDR; NR1I1; Vitamin D3 receptor; 1; 25-dihydroxyvitamin D3 receptor; Nuclear receptor subfamily 1 group I member 1;

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