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mGluR-7 (E894) Peptide

Cat no: BS1147P

mGluR-7 (E894) Peptide

The mGluR proteins (metabotropic glutamate receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-7, which can interact with PRKCABP, acts as a receptor for glutamate. It is highly expressed in various areas of the brain, but highest levels are detected in cerebellum, cerebral cortex and hippocampus.

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SPECIFICATIONS

Catalog Number

BS1147P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide mGluR-7 (E894). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q14831

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1147 mGluR-7 (E894) pAb.

Alternative Names

mGluR7; GRM7; GPRC1G; MGLUR7; GLUR7; mGlu7

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