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17b-Estradiol (Dihydrofolliculin, (17b)-Estra-1,3,5(10)-triene-3,17-diol, 3,17-Epidihydroxyestratriene, Cimara, Estrace, Estraderm, Estradot, Estring, Estrofem, Estrogel, Evorel)
17b-Estradiol (Dihydrofolliculin, (17b)-Estra-1,3,5(10)-triene-3,17-diol, 3,17-Epidihydroxyestratriene, Cimara, Estrace, Estraderm, Estradot, Estring, Estrofem, Estrogel, Evorel)
United States Biological

Potent mammalian estrogenic hormone produced by the ovary. Melting Point: 173-179 degrees C Solubility: Acetone, Alcohol, Dioxane, Storage and Stability: May...

GDC-0941 Bimesylate
GDC-0941 Bimesylate
United States Biological

Potent inhibitor of Phosphatidylinositol 3-kinase (PI3K) Form: Off-White Solid Melting Point: >280 degrees C (dec.) Solubility: DMSO

17-(Allylamino-d5) Geldanamycin
17-(Allylamino-d5) Geldanamycin
United States Biological

Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog than Geldanamycin. It induces apoptosis and displays antitumor effects....

17-(Allylamino) Geldanamycin
17-(Allylamino) Geldanamycin
United States Biological

Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog than Geldanamycin. It induces apoptosis and displays antitumor effects....

Eniluracil
Eniluracil
United States Biological

Potent inactivator of Dihydropyrimidine dehydrogenase (DPD).

FK-506 (Tacrolimus, Fujimycin)
FK-506 (Tacrolimus, Fujimycin)
United States Biological

Potent immunosuppressant (as cyclosporin A and rapamycin). Suppresses proliferation of cytotoxic T cells and inhibits the production of T cell-derived...

Anacardic acid (2-Hydroxy-6-pentadecylbenzoic acid, 6-Pentadecylsalicylic acid, AA)
Anacardic acid (2-Hydroxy-6-pentadecylbenzoic acid, 6-Pentadecylsalicylic acid, AA)
United States Biological

Potent histone acetyltransferase (HAT) inhibitor. Antibacterial. SUMOylation inhibitor. Lipoxygenase inhibitor. NF-kappaB inhibitor. Anti-tumor compound....

NETA alpha (2-(alpha-Naphthoyl)ethyltrimethylammonium iodide)
NETA alpha (2-(alpha-Naphthoyl)ethyltrimethylammonium iodide)
United States Biological

Potent fluorescent inhibitor of choline acetyltransferase. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Stable...

Thiocolchicoside (BRN 0072205, NSC 147755, Coltramyl, 10-thio-Colchicoside, 2-Demethoxy-2-glucosidoxythiocolchicine)
Thiocolchicoside (BRN 0072205, NSC 147755, Coltramyl, 10-thio-Colchicoside, 2-Demethoxy-2-glucosidoxythiocolchicine)
United States Biological

Potent competitive gamma-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist. Weak nicotinic acetylcholine receptor agonist....

Splitomicin (Splitomycin, 1,2-Dihydro-3H-naphthopyran-3-one, 1-Naphthalen propanoic acid)
Splitomicin (Splitomycin, 1,2-Dihydro-3H-naphthopyran-3-one, 1-Naphthalen propanoic acid)
United States Biological

Potent cell permeable and selective inhibitor of yeast NAD+-dependent histone deacetylase (HDAC) Sir2p. Displays higher activity in vivo than in vitro....

NU6102 (O6-Cyclohexylmethyl-2-(4-sulfamoylanilino)purine)
NU6102 (O6-Cyclohexylmethyl-2-(4-sulfamoylanilino)purine)
United States Biological

Potent CDK1/cyclin B (IC50 = 9.5 nM) and CDK2/cyclin A3 (IC50 = 5.4 nM) inhibitor. 1'000-fold more potent than NU2058. Selective for CDK1 and CDK2 compared...

Alsterpaullone (9-Nitro-7,12-dihydroindolo-benzazepin-6(5H)-one)
Alsterpaullone (9-Nitro-7,12-dihydroindolo-benzazepin-6(5H)-one)
United States Biological

Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor. Anti-tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM),...

H-8 dihydrochloride (N-5-isoquinolinesulfonamide . 2HCl)
H-8 dihydrochloride (N-5-isoquinolinesulfonamide . 2HCl)
United States Biological

Potent cAMP- and cGMP-dependent protein kinase (PKA and PKG) inhibitor. Myosin light chain kinase (MLCK) inhibitor. Tool to study protein crystal...

Mirabegron
Mirabegron
United States Biological

Potent bladder relaxant and reagent for diabetes remedy. Form: White to Off-White Solid Melting Point: 138-140 degrees C Solubility: Chloroform, Methanol

Astaxanthin (Ovoester, NSC635689, 3,3'-Dihydroxy-beta-carotene-4,4'-dione, CCRIS 7118, HSDB 7468)
Astaxanthin (Ovoester, NSC635689, 3,3'-Dihydroxy-beta-carotene-4,4'-dione, CCRIS 7118, HSDB 7468)
United States Biological

Potent antioxidant carotenoid. Free radical scavenger. Reduces oxidative stress. Anticancer compound. Anti-inflammatory. Blocks NF-kappaB activatin....

(-)-Epicatechin
(-)-Epicatechin
United States Biological

Potent antioxidant and antineoplastic agent. Atmosphere: Inert gas Melting Point: 234-237 degrees C (dec.) Solubility: DMSO, Methanol Method for Determining...

S14161 (8-Ethoxy-2-(4-fluorophenyl)-3-nitro-2H-1-benzopyran, 8-Ethoxy-2-(4-fluorophenyl)-3-nitro-2H-chromene)
S14161 (8-Ethoxy-2-(4-fluorophenyl)-3-nitro-2H-1-benzopyran, 8-Ethoxy-2-(4-fluorophenyl)-3-nitro-2H-chromene)
United States Biological

Potent antileukemia and antimyeloma compound. Apoptosis inducer. Delays tumor growth. Cyclin D2 promoter transactivation inhibitor. PI3 kinase (PI3K)...

Etoposide (VP-16-213, NSC 141540)
Etoposide (VP-16-213, NSC 141540)
United States Biological

Potent anti-cancer compound. Induces apoptosis in normal and tumor cell lines. DNA Topoisomerase II activity inhibitor. Increases Topo II-mediated DNA...

(-)-Epigallocatechin gallate (Epigallocatechin-3-gallate, CCRIS 3729, Teavigo, NVP-XAA 723)
(-)-Epigallocatechin gallate (Epigallocatechin-3-gallate, CCRIS 3729, Teavigo, NVP-XAA 723)
United States Biological

Potent anticancer compound. Anti-angiogenic. VEGF, VE-cadherin phosphorylation, matrix metalloproteinase and urokinase-plasminogen activator (uPA) inhibitor....

6-Methyl Pergolide
6-Methyl Pergolide
United States Biological

Potent antagonist of 5-HT2A and 5-HT2B receptors on porcine cardiac valves, it also activates brain dopaminergic receptors and lowers cranial DOPAC levels in...

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