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14-3-3 ? (A79) Peptide

14-3-3 ? (A79) Peptide

Cat no: BS2385P

Supplier: Bioworld Technology, Inc.
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14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 beta, gamma , E, ?, ?, 0 and o. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activities.
Catalogue number: BS2385P
Applications: Block/Neutralize/Inhibit
Swiss prot: P63104
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide 14-3-3 ? (A79). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: 14-3-3 protein zeta/delta; Protein kinase C inhibitor protein 1; KCIP-1; YWHAZ; 14-3-3 protein zeta; 14-3-3 protein delta; 14-3-3 ?; 14-3-3 delta; 1433Z; KCIP1; KCIP 1
Additional info: This peptide can be used with studies using BS2385 14-3-3 ? (A79) pAb.

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