14-3-3 E (D238) Peptide

Cat no: BS2177P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 beta, gamma , E, ?, ?, 0 and o. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activities.

Catalogue number:	BS2177P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P62258
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide 14-3-3 E (D238). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	14-3-3 protein epsilon; 14-3-3E; YWHAE; 1433E
Additional info:	This peptide can be used with studies using BS2177 14-3-3 E (D238) pAb.

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14-3-3 E (D238) Peptide

Cat no: BS2177P

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