ABL1 (E883) Peptide

Cat no: BS2513P

Supplier: Bioworld Technology, Inc.

0 reviews | Write a Review Pencil

Description
Additional Information

The Abl oncogene was initially identified as the viral transforming gene of Abelson murine leukemia virus (A-MuLV). The major translational product of c-Abl has been identified as a protein with tyrosine kinase activity and an SH2 domain. The Abl oncogene is implicated in several human leukemias including 90-95% of chronic myelocytic leukemia (CML), 20-25% of adult acute lymphoblastic leukemia (ALL) and 2-5% of pediatric ALL. In these leukemias the c-Abl proto-oncogene undergoes a (9;22) chromosomal translocation producing the Philadelphia (Ph1) chromosome. The molecular consequence of this translocation is the generation of a chimeric Bcr/c-Abl mRNA encoding activated Abl protein-tyrosine kinase. The Bcr gene has been shown to encode a GTPase-activating protein (GAP) specific for the Ras-related GTP-binding protein, p21rac.

Catalogue number:	BS2513P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P00519
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide ABL1 (E883). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	ABL1; ABL; JTK7; p150; Proto-oncogene c-Abl; Tyrosine-protein kinase ABL1; c-Abl
Additional info:	This peptide can be used with studies using BS2513 ABL1 (E883) pAb.

See Full Product Listings >

ABL1 (E883) Peptide

Cat no: BS2513P

Get Quote

About Biosave

Product Categories

Information


Get a Quote Direct from Bioworld Technology, Inc.




By submitting this form you agree to your details being passed to Bioworld Technology, Inc. for the purpose of generating the best quote*