AChR(alpha)3 (L139) pAb

Cat no: BS2851

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

The nicotinic acetylcholine receptor (nAChR) is a ligand gated ion channel that mediates neurotransmission at the neuromuscular junction, autonomic ganglia and at some sites in the central nervous system. Distinct nAChR subtypes exist that can be stimulated by the neurotransmitter acetylcholine, the natural product nicotine, or by synthetic compounds. After binding acetylcholine, Nicotinic Acetylcholine Receptor alpha 3 responds by an extensive change in conformation that affects all subunits and leads to opening of an ion conducting channel across the plasma membrane.

Catalogue number:	BS2851
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Western Blot
Size:	100ug/100ul
Swiss prot:	P32297
Dilutions:	WB: 1:500~1:1000
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 120-180 of Human AChR(alpha)3.
Species:	AChR(alpha)3 (L139) pAb detects endogenous levels of Neuronal acetylcholine receptor subunit (alpha)3 protein.
Molecular weight:	~ 60 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	Neuronal acetylcholine receptor subunit alpha-3; NACHRA3; CHRNA3
Additional info:	For research use only, not for use in diagnostic procedure.

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AChR(alpha)3 (L139) pAb

Cat no: BS2851

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