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AChR(alpha)7 pAb

AChR(alpha)7 pAb

Cat no: BS60391

Supplier: Bioworld Technology, Inc.
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Chromosome 15 encodes over 700 genes and comprises nearly 3% of the human genome. CHRFAM7A, a fusion protein comprised of FAM7A and AChR(alpha)7, is encoded by the CHRFAM7A gene, which is located on a region of human chromosome 15 that is associated with several neuropsychiatric disorders, such as schizophrenia and bipolar affective disorder. CHRFAM7A, also known as D-10 or CHRNA7, is a 412 amino acid multi-pass membrane protein that belongs to the nicotinic acetylcholine receptor (nAChR) subfamily of ligand-gated ion channel proteins, a protein superfamily that mediates signal transmission at synapses. CHRFAM7A is expressed in the hippocampus. Alternative splicing of the CHRFAM7A gene produces two splice variants.
Catalogue number: BS60391
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P36544/Q494W8
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: A synthetic peptide corresponding to residues in Human AChR(alpha)7.
Species: AChR(alpha)7 pAb detects endogenous levels of AChR(alpha)7 protein.
Molecular weight: ~ 50 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Neuronal acetylcholine receptor subunit alpha-7; CHRNA7; NACHRA7; CHRNA7-FAM7A fusion protein; CHRNA7-DR1; D-10; CHRFAM7A
Additional info: For research use only, not for use in diagnostic procedure.

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