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 Actived-Caspase-9 p35 (D315) pAb

Actived-Caspase-9 p35 (D315) pAb

Cat no: BS7070


Supplier: Bioworld Technology, Inc.
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Caspase-9 (ICE-LAP6, Mch6) is an important member of the cysteine aspartic acid protease (caspase) family. Upon apoptotic stimulation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf 1. Apaf-1 mediated activation of caspase-9 involves instrinsic proteolytic processing resulting in cleavage at Asp315 and producing a p35 subunit.
Catalogue number: BS7070
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P55211
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 300-350 of Human Caspase 9.
Species: Actived-Caspase-9 p35 (D315) pAb detects detects endogenous levels of the 35 kDa large fragment of caspase-9 following cleavage at aspartic acid 315.
Molecular weight: ~ 35 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: APAF 3,APAF-3,APAF3,Apoptosis related cysteine peptidase,Apoptotic protease activating factor 3,Apoptotic protease Mch 6,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3,CASP 9,CASP-9,CASP9, Caspase 9 apoptosis related cysteine peptidase,Caspase 9 Dominant Negative,Caspase 9c,Caspase-9, Caspase9,ICE LAP6,ICE like apoptotic protease 6,ICE-LAP6,ICE-like apoptotic protease 6,MCH6,RNCASP9
Additional info: For research use only, not for use in diagnostic procedure.

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