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Adducin (alpha) (K439) pAb

Adducin (alpha) (K439) pAb

Cat no: BS1435

Supplier: Bioworld Technology, Inc.
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Adducins are a family of cytoskeleton proteins encoded by three genes ((alpha), (beta), (gamma)). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical actin network organization. Adducin (alpha) is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin (alpha) and Adducin (gamma) is ubiquitous in contrast to the restricted expression of Adducin (beta). Adducin (beta) is expressed at high levels in brain and hematopoietic tissues, such as bone marrow, in humans, and in spleen in mice.
Catalogue number: BS1435
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P35611
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 400-450 of Human Adducin (alpha).
Species: Adducin (alpha) (K439) pAb detects endogenous levels of Adducin (alpha) protein.
Molecular weight: ~ 81 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Alpha-adducin; Erythrocyte adducin subunit alpha; ADD1; ADDA; (alpha)-Adducin; Adducin1; Adducin-1; (alpha) Adducin;
Additional info: For research use only, not for use in diagnostic procedure.

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