AIF-M1 (Y85) Peptide

Cat no: BS2407P

Supplier: Bioworld Technology, Inc.

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Description
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Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins. A novel gene, the product of which causes chromatin condensation and DNA fragmentation, was recently identified, cloned, and designated apoptosis inducing factor (AIF). Like the critical molecules, cytochrome c and caspase 9, in apoptosis, AIF localizes in mitochondria. AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase 9. AIF induces chromatin condensation and large scale DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection and apoptosis stimuli. AIF is highly conserved between human and mouse and widely expressed.

Catalogue number:	BS2407P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	O95831
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide AIF-M1 (Y85). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Apoptosis-inducing factor 1, mitochondrial; Programmed cell death protein 8; AIFM1; AIF; PDCD8
Additional info:	This peptide can be used with studies using BS2407 AIF-M1 (Y85) pAb.

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AIF-M1 (Y85) Peptide

Cat no: BS2407P

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