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ALOX5 (E267) Peptide

ALOX5 (E267) Peptide

Cat no: BS1506P

Supplier: Bioworld Technology, Inc.
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5-lipoxygenase (5-LO) is expressed primarily in polymorphonuclear leukocytes, macrophages, and mast cells. 5-LO performs the first two catalytic reactions in the biosynthesis of leukotrienes, lipid metabolites that induce contractions of airway smooth muscle and increase vascular permeability during anaphylaxis. The cellular localization of 5-LO varies between cell types. In activated blood polymorphonuclear leukocytes 5-LO undergoes calcium dependent translocation from the cytosol to the nuclear envelope. In alveolar macrophages, the majority of 5-LO is localized in the nucleus and, upon activation of these cells, intranuclear 5-LO binds to the nuclear membrane.
Catalogue number: BS1506P
Applications: Block/Neutralize/Inhibit
Swiss prot: P09917
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide ALOX5 (E267). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Arachidonate 5-lipoxygenase; 5-LO; 5-lipoxygenase; ALOX5; LOG5
Additional info: This peptide can be used with studies using BS1506 ALOX5 (E267) pAb.

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