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ANGPT4 Peptide

ANGPT4 Peptide

Cat no: BS60368P


Supplier: Bioworld Technology, Inc.
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Angiopoietin-1 (Ang-1) is a secreted ligand for Tie-2, a cell surface receptor tyrosine kinase expressed in endothelial and hemopoietic cells. Ang-1 is an angiogenic factor that mediates blood vessel maturation and may be involved in endothelial development. A related protein, angiopoietin-2 (Ang-2), is a naturally occurring antagonist of Ang-1 activation of Tie-2. In adult tissue, Ang-2 expression is restricted to sites of vascular remodeling. Ang-3 and Ang-4 represent the mouse and human counterparts of the same gene locus. The structural divergence of Ang-3 and Ang-4 cause their divergent functions. Ang-3 and Ang-4 have very different distributions in their respective species, and Ang-3 appears to act as an antagonist while Ang-4 appears to function as an agonist. Ang-3 and Ang-4 share all the main structural characteristics of Ang-1 and Ang-2 and are homologous throughout the signal peptide, N-terminal region, coiled-coil segment and Fibrinogen-like domain.
Catalogue number: BS60368P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q9Y264
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide ANGPT4. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Angiopoietin-4; ANG-4; Angiopoietin-3; ANG-3; Angiopoietin4; ANG4; Angiopoietin3; ANG3; ANG3; ANG4
Additional info: This peptide can be used with studies using BS60368 ANGPT4 pAb.

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