Annexin 5 pAb

Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. For example, the crystal structure of Annexin III has suggested a hydrophilic amino-terminus with possible Ca2+ channel activity. Similarly, Annexin V has ion channel properties. Annexin IV, also referred to as endonexin, functions to regulate Cl-flux by mediating calmodulin kinase II (CaMKII) activity and Annexin V has been shown to regulate PKC activity. Annexin V is ubiquitously expressed at high levels in tissues and cells grown in tissue culture, while Annexin VIII exhibits a more limited distribution. Where co-expressed in the same tissues, Annexin VIII is often expressed at a 100-fold lower level than Annexin V. However, Annexin VIII is preferentially expressed in acute promyelocytic leukemia (APL) cells, which may relate to its role in hematopoietic cell differentiation.

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SPECIFICATIONS

Catalog Number

BS6525

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Recombinant full length Human Annexin 5.

Species

ANXA5 pAb detects endogenous levels of ANXA5 protein.

Dilutions

WB: 1:500~1:2000\nIHC: 1:50~1:200

Swiss Prot

P08758

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 36 kDa

Alternative Names

Anchorin CII antibodyAnnexin 5 antibodyAnnexin A5 antibodyAnnexin V antibodyAnnexin-5 antibodyAnnexin5 antibodyAnnexinA5 antibodyAnnexinV antibodyANX 5 antibodyANX A5 antibodyANX5 antibodyANXA5 antibodyANXA5 antibodyCalphobindin I antibodyCBP I antibodyCBP-I antibodyEndonexin II antibodyENX 2 antibodyENX2 antibodyLipocortin V antibodyPAP I antibodyPAP-I antibodyPlacental anticoagulant protein 4 antibodyPlacental anticoagulant protein I antibodyPP 4 antibodyPP4 antibodyThromboplastin inhibi