Home  >  Products  >  Apaf-1-ALT (H324) Peptide
Apaf-1-ALT (H324) Peptide

Apaf-1-ALT (H324) Peptide

Cat no: BS1016P

Supplier: Bioworld Technology, Inc.
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
APAF-1-ALT harbors the caspase recruitment domain and an incomplete CED-4 like/ATPase domain, but lacks the WD-40 repeat units. The LNCaP cell expressed the full-length APAF-1 weakly and APAF-1-ALT rather abundantly, especially after mycoplasma infection. LNCaP underwent a retarded DNA damage-induced apoptosis, which was independent of caspase 9 activity. APAF-1-ALT functioned less effectively in inducing apoptosis than did APAF-1-XL, the full-length APAF-1, in transient transfection. Moreover, APAF-1-ALT interfered with APAF-1-XL's ability to induce apoptosis in transient double transfection experiment. These results indicate that APAF-1-ALT is a molecule that is deficient and impeded for mediating apoptosis and that it may contribute to the resistance to DNA damage-induced treatment observed in LNCaP.
Catalogue number: BS1016P
Applications: Block/Neutralize/Inhibit
Swiss prot: O14727-6
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Apaf-1-ALT (H324). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Apaf-1 Isoform 6; APAF1 Isoform 6;
Additional info: This peptide can be used with studies using BS1016 Apaf-1-ALT (H324) pAb.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
Bioworld Technology, Inc.
Get a Quote Direct from
Bioworld Technology, Inc.

By submitting this form you agree to your details being passed to Bioworld Technology, Inc. for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave