APCS pAb

Cat no: BS6527

Supplier: Bioworld Technology, Inc.

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Serum amyloid P (SAP) is a glycoprotein belonging to the pentraxin family of proteins, which has a characteristic pentameric organization and calcium-dependent ligand binding. Secreted by liver epithelial cells, SAP is found in serum and urine. Although the function of SAP has not been clearly established, it has been shown to interact with DNA and histones and is thought to play a role in scavenging nuclear material released from damaged circulating cells. Also designated PTX2, SAP is a precursor of the protein amyloid P component (AP), which is universally associated with the amyloid deposits in all forms of amyloidoses, including Alzheimer's disease. SAP is a decamer of 10 identical, noncovalently linked subunits, each of which may be posttranslationally modified by glycosylation.

Catalogue number:	BS6527
Reactivities:	Human
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	P02743
Dilutions:	WB: 1:500~1:2000 IHC: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Recombinant full length Human APCS.
Species:	APCS pAb detects endogenous levels of APCS protein.
Molecular weight:	~ 25 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	9.5S alpha 1 glycoprotein; 9.5S alpha-1-glycoprotein; Amyloid P component serum; APCS; MGC88159; Pentaxin related; Pentraxin 2; PTX 2; PTX2; SAMP; SAP; Serum amyloid P component; Serum amyloid P-component(1-203);
Additional info:	For research use only, not for use in diagnostic procedure.

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APCS pAb

Cat no: BS6527

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