APRIL (S183) Peptide

Cat no: BS1893P

Supplier: Bioworld Technology, Inc.

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A proliferation-inducing ligand (APRIL), also designated TNFSF13, is a Type II membrane protein that shares characteristics with other members of the tumor necrosis factor (TNF) cytokine family. APRIL is expressed in high levels in transformed cell lines and in human colon, thyroid, and lymphoid tumor tissues. APRIL is critically involved in the regulation of infections, inflammation, autoimmune diseases, and tissue homeostasis. APRIL is implicated in the regulation of tumor cell growth. The C-terminal extracellular domain has b jelly roll topography and is important in ligand trimerization. The binding of the ligand to its respective receptor induces oligomerization, initiating downstream signaling events. Intrinsic to oligomerization is the formation of the receptor binding site at the junction between neighboring subunits, creating a multivalent ligand.

Catalogue number:	BS1893P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	O75888
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide APRIL (S183). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Tumor necrosis factor ligand superfamily member 13; A proliferation-inducing ligand; APRIL; TNF- and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1; TRDL1; CD256; TNFSF13; APRIL; TALL2; ZTNF2; ORF Names: UNQ383/PRO715
Additional info:	This peptide can be used with studies using BS1893 APRIL (S183) pAb.

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APRIL (S183) Peptide

Cat no: BS1893P

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