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Arfaptin 1 (K314) Peptide

Arfaptin 1 (K314) Peptide

Cat no: BS3076P

Supplier: Bioworld Technology, Inc.
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Arfaptin 1 is an ARF binding protein that inhibits PLD activation, vesicular trafficking and secretion. In the present report, we show that arfaptin 1 interacts with 'high speed' membranes independently of ARF. However, addition of myristoylated ARF3 (myrARF3) increases the association of arfaptin 1 with the membranes, suggesting that arfaptin 1 and ARF form a complex on the Golgi. Utilizing several deletion mutants of arfaptin 1 it is shown that the association of arfaptin 1 with myrARF3 is mediated via two binding sites on arfaptin 1. These two domains are needed for arfaptin 1 inhibition of PLD activation by myrARF3 in vitro.
Catalogue number: BS3076P
Applications: Block/Neutralize/Inhibit
Swiss prot: P53367
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Arfaptin 1 (K314). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Arfaptin-1; ADP-ribosylation factor-interacting protein 1; ARFIP1; Arfaptin1
Additional info: This peptide can be used with studies using BS3076 Arfaptin 1 (K314) pAb.

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