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ARHGDIG pAb

ARHGDIG pAb

Cat no: BS5899

Supplier: Bioworld Technology, Inc.
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The Ras superfamily of small GTP-binding proteins are critical mediators of diverse cell signaling pathways, including those leading to proliferation, cytoskeletal organization and secretion. The counter-conversion of the active GTPbound form of these proteins to their inactive GDP-bound form is influenced by two types of regulatory proteins: those that alter the intrinsic GTPase activity of the GTP-binding proteins and those that alter the rate of GDP/GTP exchange. Guanine nucleotide-releasing factors (GRFs) increase the GDP dissociation rate, while GDP-dissociation inhibitors (GDIs) decrease the dissociation rate. The Rho GDI subfamily is composed of Rho GDI(alpha), Ly-GDI (also known as Rho GDI(beta) and previously known as GDI/D4) and Rho GDI(gamma). The Rho GDI proteins interact with and have varying affinities for several Ras-like GTP binding proteins, including Rho A, Rho B, Rac and Cdc42. Ly-GDI is expressed only in hematopoietic cells, predominantly in B and T lymphocyte cell lines.
Catalogue number: BS5899
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: Q99819
Dilutions: WB: 1:500~1:1000 ICC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 176-221 of Human ARHGDIG.
Species: ARHGDIG pAb detects endogenous levels of ARHGDIG protein.
Molecular weight: ~ 25 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Rho GDP-dissociation inhibitor 3; Rho GDI 3; Rho-GDI gamma; Rho GDI(gamma); Rho-GDI(gamma)
Additional info: For research use only, not for use in diagnostic procedure.

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