ARHGDIG Peptide

Cat no: BS5899P

Supplier: Bioworld Technology, Inc.

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The Ras superfamily of small GTP-binding proteins are critical mediators of diverse cell signaling pathways, including those leading to proliferation, cytoskeletal organization and secretion. The counter-conversion of the active GTPbound form of these proteins to their inactive GDP-bound form is influenced by two types of regulatory proteins: those that alter the intrinsic GTPase activity of the GTP-binding proteins and those that alter the rate of GDP/GTP exchange. Guanine nucleotide-releasing factors (GRFs) increase the GDP dissociation rate, while GDP-dissociation inhibitors (GDIs) decrease the dissociation rate. The Rho GDI subfamily is composed of Rho GDIalpha, Ly-GDI (also known as Rho GDIbeta and previously known as GDI/D4) and Rho GDIgamma . The Rho GDI proteins interact with and have varying affinities for several Ras-like GTP binding proteins, including Rho A, Rho B, Rac and Cdc42. Ly-GDI is expressed only in hematopoietic cells, predominantly in B and T lymphocyte cell lines.

Catalogue number:	BS5899P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q99819
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide ARHGDIG. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Rho GDP-dissociation inhibitor 3; Rho GDI 3; Rho-GDI gamma; Rho GDIgamma ; Rho-GDIgamma
Additional info:	This peptide can be used with studies using BS5899 ARHGDIG pAb.

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ARHGDIG Peptide

Cat no: BS5899P

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