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ARHGEF10 pAb

ARHGEF10 pAb

Cat no: BS5619


Supplier: Bioworld Technology, Inc.
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ARHGEF10 (rho guanine nucleotide exchange factor 10), also known as GEF10 or KIAA0294, is a 1,369 amino acid protein that contains one DBL-homology domain and is thought to play a role in myelination of peripheral nerves, specifically during development. ARHGEF10 is expressed as four alternatively spliced isoforms that are present at low levels in ovary, lung, testis and kidney, with considerably higher expression in the central and peripheral nervous systems. Defects in the gene encoding ARHGEF10 are the cause of slowed nerve conduction velocity (SNCV), an autosomal dominant disorders that is characterized by a reduction in nerve velocities resulting from lack of proper myelination.
Catalogue number: BS5619
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: O15013
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: A synthetic peptide corresponding to residues in Human ARHGEF10.
Species: ARHGEF10 pAb detects endogenous levels of ARHGEF10 protein.
Molecular weight: ~ 152 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Rho guanine nucleotide exchange factor 10; ARHGEF10; KIAA0294
Additional info: For research use only, not for use in diagnostic procedure.

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