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Arrestin-C (E374) Peptide

Cat no: BS2394P

Arrestin-C (E374) Peptide

Members of Arrestin/beta-Arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters or sensory signals. Arrestin-C, also known as retinal cone Arrestin-3, X-Arrestin or cArr, is a member of the Arrestin family of proteins. It is predominantly found in the retina and pineal gland and localizes to the inner and outer segments of red-, green- and blue-cone photoreceptors and the inner plexiform regions. Two Arrestin-C isoforms exist due to alternative splicing. Isoform 1 is the mature full length protein and isoform 2 is truncated, ending with an arginine for amino acid residue 359. Arrestin-C expression is stimulated by retinoic acid. It may play a role in retina-specific signal transduction and bind to photoactivated-phosphorylated red/green opsins. In addition, Arrestin-C forms homodimers and oligomers with beta-Arrestins and may regulate beta-Arrestin mediated signaling.

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SPECIFICATIONS

Catalog Number

BS2394P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Arrestin-C (E374). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P36575

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2394 Arrestin-C (E374) pAb.

Alternative Names

Arrestin-C; Arrestin C; ArrestinC; Cone arrestin; C-arrestin; cArr; Retinal cone arrestin-3; X-arrestin; ARR3; ARRX; CAR

SUPPLIER INFO

Bioworld Technology, Inc.

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