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Arrestin-C (E374) Peptide

Arrestin-C (E374) Peptide

Cat no: BS2394P


Supplier: Bioworld Technology, Inc.
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Members of Arrestin/beta-Arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters or sensory signals. Arrestin-C, also known as retinal cone Arrestin-3, X-Arrestin or cArr, is a member of the Arrestin family of proteins. It is predominantly found in the retina and pineal gland and localizes to the inner and outer segments of red-, green- and blue-cone photoreceptors and the inner plexiform regions. Two Arrestin-C isoforms exist due to alternative splicing. Isoform 1 is the mature full length protein and isoform 2 is truncated, ending with an arginine for amino acid residue 359. Arrestin-C expression is stimulated by retinoic acid. It may play a role in retina-specific signal transduction and bind to photoactivated-phosphorylated red/green opsins. In addition, Arrestin-C forms homodimers and oligomers with beta-Arrestins and may regulate beta-Arrestin mediated signaling.
Catalogue number: BS2394P
Applications: Block/Neutralize/Inhibit
Swiss prot: P36575
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Arrestin-C (E374). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Arrestin-C; Arrestin C; ArrestinC; Cone arrestin; C-arrestin; cArr; Retinal cone arrestin-3; X-arrestin; ARR3; ARRX; CAR
Additional info: This peptide can be used with studies using BS2394 Arrestin-C (E374) pAb.

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