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Asterric Acid (Dimethylosoic acid, Antibiotic TAN 1415A, Antibiotic WF 12880A)

Cat no: A3884

Asterric Acid (Dimethylosoic acid, Antibiotic TAN 1415A, Antibiotic WF 12880A)

A fungal metabolite, asterric acid is isolated from a number of Aspergillus and Penicillium species. It is an inhibitor of vascular endothelial growth factor (VEGF). Asterric acid is an angiogenesis inhibitor acting on VEGF-induced tube formation of human umbilical vein endothelial cells.\n\nPurity: >99% by HPLC\n\nSolubility: Soluble in ethanol, methanol, DMF or DMSO.

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SPECIFICATIONS

Catalog Number

A3884

Size

1mg

Purity

>99% by HPLC

References

1. Fungal metabolites, asterric acid derivatives inhibit vascular endothelial growth factor (VEGF)-induced \ntube formation of HUVECs. Lee H.J. et al. J. Antibiot. 2002, 55, 552. \n2. Asterric acid, a new endothelin binding inhibitor. Ohashi H. et al. J. Antibiot. 1992, 45, 1684. \n3. Studies in the biochemistry of micro-organisms. 115. Metabolites of Penicillium frequentans Westling: \nisolation of sulochrin, asterric acid, (+)-bisdechlorogeodin and two new substituted anthraquinones, \nquestin and questinol. Mahmoodian A. et al. Biochem. J. 1964, 92, 369.

Alternative Names

Dimethylosoic acid, Antibiotic TAN 1415A, Antibiotic WF 12880A

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Applications

ELISA

Reactivities

Hum

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Applications

IF

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Mouse

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Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

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Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

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Applications

ELISA, FC, IHC, WB

Hosts

Mouse

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Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

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Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

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