Ataxin-2 (F774) Peptide

Cat no: BS3811P

Supplier: Bioworld Technology, Inc.

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Additional Information

Ataxin-2, the gene product of the human spinocerebellar ataxia type 2 (SCA2/ATXN2) gene, is a basic protein with two domains (Sm1 and Sm2) implicated in RNA splicing and protein interaction. Ataxin-2 interacts with a putative RNA-binding protein ataxin-2-binding-protein 1 (A2BP1), which is expressed in muscle and brain. Ataxin-2 is ubiquitously expressed with highest levels in the cytoplasm of Purkinje cells. Both A2BP1 and ataxin-2 are localized to the trans-Golgi network. Mice expressing ataxin-2 with polyglutamine show progressive functional deficits accompanied by loss of Purkinje cell dendritic arbor and eventually loss of Purkinje cells. In conclusion, expansion of ataxin-2 results in spinocerebellar ataxia type 2, which affects the cerebellum and other areas of the central nervous system.

Catalogue number:	BS3811P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q99700
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide Ataxin-2 (F774). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Ataxin 2; ATXN2; SCA2; TNRC13;
Additional info:	This peptide can be used with studies using BS3811 Ataxin-2 (F774) pAb.

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Ataxin-2 (F774) Peptide

Cat no: BS3811P

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