Atrophin-1 Peptide

Cat no: BS5625P

Supplier: Bioworld Technology, Inc.

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Dentatorubral-pallidoluysian atrophy protein, also designated atrophin-1, interacts with several other proteins, including RERE, BAIAP2 and WWP1-3. It is highly expressed in ovary, testis, brain and prostate, but can also be detected in thymus, liver and leukocytes. Defects in ATN1, the gene encoding for the atrophin protein, can cause dentatorubral-pallidoluysian atrophy (DRPLA) or Haw River syndrome (HRS). Both disorders are dominant neurodegenerative disorders caused by an increase in the number of polyglutamine (Gln) repeats in the ATN1 gene (7-23 repeats in the normal population, 49-75 in patients affected by DRPLA or HRS). More repeats corresponds to earlier onset and more severe clinical manifestations of the diseases. DRPLA is characterized by a loss of neurons in the dentate nucleus, rubrum, globus pallidus and Luys

Catalogue number:	BS5625P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P54259
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide Atrophin-1. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Atrophin1; Atrophin 1; Dentatorubral-pallidoluysian atrophy protein; ATN1; D12S755E; DRPLA
Additional info:	This peptide can be used with studies using BS5625 Atrophin-1 pAb.

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Atrophin-1 Peptide

Cat no: BS5625P

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