BIK pAb

Cat no: BS7251

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

Bik/Nbk (Bcl-2-interacting killer/natural born killer) is a potent pro-apoptotic protein belonging to a group of Bcl-2 family members that includes Bad, Bid, Bim, Hrk, and Noxa, containing a BH3 domain but lacking other conserved domains, BH1 or BH2. Functionally, Bik is able to bind to and antagonize anti-apoptotic Bcl-2 family members including Bcl-2, Bcl-xL, and viral homologs E1B-19K and EBV-BHFR1. The BH3 domain of Bik is essential for its apoptotic activity and interaction with survival proteins . Phosphorylation of Bik is correlated with an increase in its pro-apoptotic activity.

Catalogue number:	BS7251
Reactivities:	Human
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	Q13323
Dilutions:	WB:1:500~2000 IHC:1:50~200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Recombinant full length Human BIK.
Species:	BIK pAb detects endogenous levels of BIK protein.
Molecular weight:	~ 18 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	BP4; NBK; BIP1; Bcl-2-interacting killer; Apoptosis inducer NBK;
Additional info:	For research use only, not for use in diagnostic procedure.

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BIK pAb

Cat no: BS7251

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