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Bim (A2) Peptide

Bim (A2) Peptide

Cat no: BS1035P

Supplier: Bioworld Technology, Inc.
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Pro-apototic Bcl-2 family members promote cell death by neutralizing their anti-apoptotic relatives, which otherwise maintain cell viability by regulating caspase activity. Bim belongs to the BH3-only subgroup of Bcl-2 related proteins and exists in three distinct isoforms, BimS (short), BimL (long) and BimEL (extra long). ERK1/2 phosphorylates BimEL, resulting in rapid degradation of the isoform via the proteasome pathway. At least three sites for ERK1/2 phosphorylation exist on BimEL, whereas ERK1/2 does not effect BimS or BimL, implying a unique role for BimEL in cell survival signaling.
Catalogue number: BS1035P
Applications: Block/Neutralize/Inhibit
Swiss prot: O43521
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Bim (A2). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Bcl2-interacting mediator of cell death; BIM; BIM
Additional info: This peptide can be used with studies using BS1035 Bim (A2) pAb.

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