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BLNK (N91) Peptide

BLNK (N91) Peptide

Cat no: BS2547P


Supplier: Bioworld Technology, Inc.
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B-cell linker protein (BLNK, also known as SLP65, BASH, and BCA) is a B cell adaptor that plays an important role in B cell development and in BCR-signal transduction. Since BLNK does not encode any intrinsic enzymatic activity, its function is to serve as a scaffold for assembling macromolecular complexes which includes enzymes (PLC gamma, Vav and Btk) and additional linker proteins (Grb2 and Nck) (1-3) . In addition, BLNK binds Btk and is required for activation of the transcription factor NF-kB. Tyrosine phosphorylation of BLNK by Syk provides specific docking sites for these SH2-containing effector proteins which in turn permits phosphorylation and/or activation of their respective signaling pathways.
Catalogue number: BS2547P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q8WV28
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide BLNK (N91). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: B-cell linker protein; BASH; BASH; Bca; Bca; BLNK; BLNK s; BLNK; Cytoplasmic adapter protein; Ly 57; Ly 57; Ly57; Lymphocyte antigen 57; Lymphocyte antigen 57; Lyw 57; Lyw57; Lyw57; MGC111051; SLP 65; SLP 65; SLP-65; SLP65;
Additional info: This peptide can be used with studies using BS2547 BLNK (N91) pAb.

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