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BMI1 pAb

BMI1 pAb

Cat no: BS6015


Supplier: Bioworld Technology, Inc.
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Mel-18 and Bmi-1 are mammalian homologs of Drosophila Pc-g group proteins, as they are similarly expressed during development and implicated in the regulation of gene expression, axial skeleton development, and the control of proliferation and survival of hematopoietic cells. Bmi-1 has been identified as a potent oncogene as it contributes to the transcriptional activation of genes implicated in early lymphoid development. Proviral activation of Bmi-1 expression corresponds to enhanced gene-specific activation of other proto-oncogenes, including c-Myc and Pim, subsequently resulting in the progression of lymphomagenesis.
Catalogue number: BS6015
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P35226
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human BMI1.
Species: BMI1 pAb detects endogenous levels of BMI1 protein.
Molecular weight: ~ 37 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Polycomb complex protein BMI-1; Polycomb group RING finger protein 4; RING finger protein 51; BMI1; PCGF4; RNF51
Additional info: For research use only, not for use in diagnostic procedure.

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