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BMP-3 (E306) pAb

BMP-3 (E306) pAb

Cat no: BS3683

Supplier: Bioworld Technology, Inc.
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Bone morphogenic proteins (BMPs) are members of the TGF(beta) superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGF(beta) receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.
Catalogue number: BS3683
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P12645
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 261-310 of Human BMP-3.
Species: BMP-3 (E306) pAb detects endogenous levels of BMP-3 protein.
Molecular weight: ~ 54 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Bone morphogenetic protein 3; BMP-3; Bone morphogenetic protein 3A; BMP-3A; Osteogenin; BMP3A; BMP3
Additional info: For research use only, not for use in diagnostic procedure.

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