BMPR1B pAb

Cat no: BS6534

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Two type I receptors have been characterized, BMPR-IA (also designated SKR5, ALK-3, and BRK-1) and BMPR-IB (also designated ALK-6 and SKR 6), that bind to bone morphogenetic proteins (BMP)-2, BMP-4, and osteogenic protein (OP)-1 (also designated BMP-7). BMPR-IA and BMPR-IB are both expressed in human glioma cell lines. The type II receptor, BMPR-II, efficiently binds to OP-1 and BMP-2 and weakly binds BMP-4, and it is widely expressed in different tissues, including brain. The BMP receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morphogenesis in a dose dependent fashion.

Catalogue number:	BS6534
Reactivities:	Human, Mouse
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	O00238
Dilutions:	WB: 1:500~1:2000 IHC: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Recombinant full length Human BMPR1B.
Species:	BMPR1B pAb detects endogenous levels of BMPR1B protein.
Molecular weight:	~ 57 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	Activin receptor like kinase 6; Acvrlk6; ALK 6; ALK6; alk6tr; BMP type-1B receptor; BMPR IB; BMPR-1B; Bmpr1b; BMPRIB; BMR1B; Bone morphogenetic protein receptor type 1B; Bone morphogenetic protein receptor type IB; Bone morphogenetic protein receptor type-1B; BR 1b; BR1b; CDw 293; CDw293; CDw293 antigen; CFK 43a; CFK43a; Serine/threonine receptor kinase; zALK 6; zALK6;
Additional info:	For research use only, not for use in diagnostic procedure.

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BMPR1B pAb

Cat no: BS6534

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