BNIP-2 pAb

Cat no: BS5630

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins.

Catalogue number:	BS5630
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Immunofluorescence, Western Blot
Size:	100ug/100ul
Swiss prot:	Q12982
Dilutions:	WB: 1:500~1:1000 IF: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 269-314 of Human BNIP-2.
Species:	BNIP-2 pAb detects endogenous levels of BNIP-2 protein.
Molecular weight:	~ 36 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2; BNIP2; BNIP 2; NIP2
Additional info:	For research use only, not for use in diagnostic procedure.

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BNIP-2 pAb

Cat no: BS5630

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