BST1 pAb

BST-1 (bone marow stromal antigen-1) has been identified as a surface molecule that is GPI-anchored to the cell membrane of stromal cells. Both ADP-ribosyl cyclase and cADPR hydrolase activites have been demonstrated by BST-1. cADPR activity is a potential regulator of insulin secretion in pancreatic beta cells. Most pancreatic islet cells express BST-1, indicating a link between BST-1 and insulin secretion. BST-1 expression has also been found in a wide range of tissues including umbilical vein endothelial cells, monocytes and granulocytes. BST-1 expression in thymus tissue and on B and T cell progenitors undergoing gene rearrangement implicates BST-1 as a useful marker for lymphoid progenitor cells that are initiating gene rearrangement of their antigen receptors. BST-1 has also been shown to facilitate B cell growth and may act as a receptor.

Prices direct from Bioworld Technology, Inc.

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

BS5633

Size

100ug/100ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 120-165 of Human BST1.

Species

BST1 pAb detects endogenous levels of BST1 protein.

Dilutions

WB: 1:500~1:1000\nICC: 1:50~1:200

Swiss Prot

Q10588

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul