BTB and CNC homology 1(BACH1, basic leucine zipper transcription factor 1, HA2303, Transcription regulator protein BACH1)

BACH1 (BTB and CNC homolog 1; also basic leucine zipper transcription factor 1) is a \nubiquitously expressed member of the Bach family of transcription factors. Although its predicted MW is 82kD, it runs anomalously at 110kD in SDS-PAGE. BACH1 forms noncovalent homodimers, and heterodimers with Maf oncoproteins and p53-related proteins. It apparently serves as an architectural component for gene regulatory protein complexes. Mouse BACH1 is 739 amino acids (aa) in length. It contains a protein-interaction BTB domain (aa24-127), a DNA-binding motif (aa565-580), and a Leu-zipper domain (aa588-610). This molecule should not be confused with Bach1/Fancj/Brip1 helicase. Over aa133-513, mouse BACH1 shares 75% and 88% aa identity with human and rat BACH1, respectively. \n\nApplications:\nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot:1ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute by adding sterile 40-50% glycerol, PBS, 0.02% sodium azide. Aliquot and store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts