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BTRC pAb

BTRC pAb

Cat no: BS6777


Supplier: Bioworld Technology, Inc.
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(beta)-TrCP (beta-tranducin repeats containing protein), also designated E3RSIkB or FWD1, and HOS (homologous to Slimb) are F-box proteins that function as substrate recognition subunits of ubiquitin ligases. HOS and (beta)-TrCP differ in their amino terminal regions, but exhibit high homology within the F-box and WD40 repeat-containing regions. (beta)-TrCP mediates ubiquitin/proteasome-dependent degradation of CD4 and ubiquitination of various proteins including IkB and (beta)-catenin. HOS has also been shown to regulate the degradation of IkB and (beta)-catenin in a similar manner.
Catalogue number: BS6777
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q9Y297
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human BTRC.
Species: BTRC pAb detects endogenous levels of BTRC protein.
Molecular weight: ~ 68 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Beta transducin repeat containing E3 ubiquitin protein ligase; beta TrCP1; beta-transducin repeat containing; BETA-TRCP; betaTrCP; BTRC; bTrCP; bTrCP1; E3RSIkappaB; F box and WD repeat protein 1B; F box and WD repeats protein beta TrCP; F-box and WD repeats protein beta-TrCP; F-box/WD repeat protein 1A; F-box/WD repeat-containing protein 1A; FBW1A; FBW1A; FBXW1; FBXW1A; FWD1; HOS; mKIAA4123; pIkappaBalpha-E3 receptor subunit; Slimb;
Additional info: For research use only, not for use in diagnostic procedure.

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