C/EBP-(beta) (V259) pAb

Cat no: BS1942

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

C/EBP (beta) is a member of the C/EBP transcription factor family. The C/EBP (beta) gene encodes several isoforms, which have truncated transcription activation domains by the alternative translational initiation at multipe AUG start sites. Initiation of translation at the in-frame AUGs forms four C/EBP (beta) isoforms. C/EBP (beta) is also known as interleukin 6-dependent DNA-binding protein (IL6DBP), liver activator protein(LAP) or liver-enriched transcriptional activator protein transcription factor 5 (TCF5). C/EBP (beta) contributes to the regulation of the acute phase response in hepatocytes. Stat3 has an important function in IL-6-mediated transcription of the C/EBP (beta) gene that has direct implication for acute phase response in liver cells.The 35 kDa C/EBP (beta) form requires phosphorylation for its DNA binding ability, and increased binding of C/EBP (beta) isoforms during acute-phase reaction occurs through its upregulation and structural modification.

Catalogue number:	BS1942
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	P17676
Dilutions:	WB: 1:500~1:1000 IHC: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 220-270 of Human C/EBP-(beta).
Species:	C/EBP-(beta) (V259) pAb detects endogenous levels of total C/EBP-(beta) protein.
Molecular weight:	~ 19, 36, 38 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	CCAAT/enhancer-binding protein beta; C/EBP (beta); C/EBP(beta); C/EBP beta; Liver activator protein; LAP; Liver-enriched inhibitory protein; LIP; Nuclear factor NF-IL6; Transcription factor 5; TCF-5; CEBPB; TCF5; ORF Names: PP9092
Additional info:	For research use only, not for use in diagnostic procedure.

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C/EBP-(beta) (V259) pAb

Cat no: BS1942

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