C/EBP-E (K220) pAb

C/EBP (alpha) regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP (alpha) uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic (alpha) helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP (alpha) appears to function exclusively in terminally-differentiated, growth-arrested cells. Additional family members include C/EBP (beta), C/EBP (gamma), C/EBP (delta) and C/EBP E, all of which exhibit similar DNA-binding specificities and affinities to C/EBP (alpha). Furthermore, C/EBP (beta) and C/EBP (delta) readily form heterodimers both with each other as well as with C/EBP (alpha).

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SPECIFICATIONS

Catalog Number

BS2074

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 188-245 of Human C/EBP-E.

Species

C/EBP-E (K220) pAb detects endogenous levels of C/EBP-E protein.

Dilutions

WB: 1:500~1:1000\nIHC: 1:50~1:200

Swiss Prot

Q15744

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul