C5aR (S334) Peptide

Cat no: BS1522P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

C5a receptor (C5aR), also known as CD88, is a G protein-coupled integral membrane protein. CD88, which is expressed on neutrophils, monocytes, macrophages, hepatocytes and mast cells, as well as on various epithelial and endothelial cells, serves as a receptor for the inflammatory peptide C5a. Research studies suggest a role for CD88 in the inflammatory response. The binding of C5a to CD88 has been shown to elicit increased production of acute phase proteins in liver. In brain, an increased production of CD88 has been shown to be associated with inflammation. Research also indicates a role for C5a/C5aR in the pathogenesis of rheumatoid arthritis, as well as a heightened responsiveness of human bronchial epithelial cells (HBECs) to C5a upon exposure of these cells to cigarette smoke and other environmental irritants.

Catalogue number:	BS1522P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P21730
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide C5aR (S334). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD88; C5AR1; C5AR; C5R1
Additional info:	This peptide can be used with studies using BS1522 C5aR (S334) pAb.

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C5aR (S334) Peptide

Cat no: BS1522P

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