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CA6 pAb

CA6 pAb

Cat no: BS5637


Supplier: Bioworld Technology, Inc.
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Carbonic anhydrase VI (CA VI) contributes to taste function when secreted in the saliva by protecting taste receptor cells (TRCs) from apoptosis. Functional CA VI exists as a single polypeptide chain tightly bound to one molecule of zinc, and containing two N-linked glycosylation sites. Decreased CA VI secretion correlates with loss of taste (hypogeusia) and smell (hyposmia) or distorted taste (dysgeusia) and smell (dysosmia), and altered taste bud morphology. Addition of zinc to individuals experiencing these symptoms restored secretion of CA VI to normal levels and normal taste bud morphology in some, but not all, cases, indicating two different mechanisms leading to CA VI dysfunction.
Catalogue number: BS5637
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P23280
Dilutions: WB: 1:500~1:1000 ICC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to the 263-308 of Human CA6.
Species: CA6 pAb detects endogenous levels of Carbonic anhydrase 6 protein.
Molecular weight: ~ 37 kDa (glycosylated) ~ 33 kDa (deglycosylated)
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Carbonic anhydrase 6; Carbonic anhydrase6; Carbonate dehydratase VI; Carbonic anhydrase VI; CA-VI; Salivary carbonic anhydrase; Secreted carbonic anhydrase; CA-6
Additional info: For research use only, not for use in diagnostic procedure.

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